By performing the equivalent of autopsies on... - Wissenschaft und Deutsch (on Hiatus)
By performing the equivalent of autopsies on bacteria, researchers have developed a new method for developing & characterizing new potential antibiotics. The approach combines microscopy & quantitative biology tools and is the first time that a single test can be performed and identify the likely mechanism of action for a new chemical or compound. The method has also been miniaturized so that only a few nanograms of each chemical candidate is required.More info: http://bit.ly/14aQe0TPublication: Bacterial cytological profiling rapidly identifies the cellular pathways targeted by antibacterial molecules. PNAS, 2013 DOI: 10.1073/pnas.1311066110Image: False-colored SEM of a human neutrophil ingesting MRSAImage credit: NIAID
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By performing the equivalent of autopsies on bacteria, researchers have developed a new method for developing & characterizing new potential antibiotics. The approach combines microscopy & quantitative biology tools and is the first time that a single test can be performed and identify the likely mechanism of action for a new chemical or compound. The method has also been miniaturized so that only a few nanograms of each chemical candidate is required.

More info: http://bit.ly/14aQe0T
Publication: Bacterial cytological profiling rapidly identifies the cellular pathways targeted by antibacterial molecules. PNAS, 2013 DOI: 10.1073/pnas.1311066110

Image: False-colored SEM of a human neutrophil ingesting MRSA
Image credit: NIAID

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