By performing the equivalent of autopsies on bacteria, researchers have developed a new method for developing & characterizing new potential antibiotics. The approach combines microscopy & quantitative biology tools and is the first time that a single test can be performed and identify the likely mechanism of action for a new chemical or compound. The method has also been miniaturized so that only a few nanograms of each chemical candidate is required.
More info: http://bit.ly/14aQe0T
Publication: Bacterial cytological profiling rapidly identifies the cellular pathways targeted by antibacterial molecules. PNAS, 2013 DOI: 10.1073/pnas.1311066110
Image: False-colored SEM of a human neutrophil ingesting MRSA
Image credit: NIAID