Bacterial Supernova Tal Danino, Jeff Hasty, and... - Wissenschaft und Deutsch
Bacterial Supernova
Tal Danino, Jeff Hasty, and Sangeeta BhatiaKoch Institute at MIT and UC San Diego
Programming E. coli to Release Drugs into a Tumor.One might imagine a bacterium as a simple, solitary cell doing all that it can to survive and reproduce. But many bacteria are social creatures; by using a process called quorum sensing, they communicate and alter their behaviors as a group. This intelligent decision-making system inspired MIT researchers to ask an unusual question: can we “hack” bacteria and use them to treat cancer?
Image: Here, they have rewired a colony of E. coli to produce a burst of fluorescent protein when it reaches a predetermined density. The researchers hope to modify this system and engineer the bacteria to release a coordinated burst of drugs at a tumor site.
source

Bacterial Supernova

Tal Danino, Jeff Hasty, and Sangeeta Bhatia
Koch Institute at MIT and UC San Diego

Programming E. coli to Release Drugs into a Tumor.One might imagine a bacterium as a simple, solitary cell doing all that it can to survive and reproduce. But many bacteria are social creatures; by using a process called quorum sensing, they communicate and alter their behaviors as a group. This intelligent decision-making system inspired MIT researchers to ask an unusual question: can we “hack” bacteria and use them to treat cancer?

Image: Here, they have rewired a colony of E. coli to produce a burst of fluorescent protein when it reaches a predetermined density. The researchers hope to modify this system and engineer the bacteria to release a coordinated burst of drugs at a tumor site.

source

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